عنوان	A novel electrochemical sensor based on metal-organic framework for electro-catalytic oxidation of L-cysteine
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	Metal-organic frameworks Gold nanoparticles Electrochemistry Electrochemical sensors L-cysteine
چکیده	A novel electrochemical sensor based on Au-SH-SiO2 nanoparticles supported on metal-organic framework (Au-SH-SiO2@Cu-MOF) has been developed for electrocatalytic oxidation and determination of L-cysteine. The Au-SH-SiO2@Cu-MOF was characterized by scanning electron microscopy, transmission electron microscopy, x-ray diffraction and cyclic voltammetry. The electrochemical behavior of L-cysteine at the Au-SH-SiO2@Cu-MOF was investigated by cyclic voltammetry. The Au-SH-SiO2@Cu-MOF showed a very efficient electrocatalytic activity for the oxidation of L-cysteine in 0.1 M phosphate buffer solution (pH 5.0). The oxidation overpotentials of L-cysteine decreased significantly and their oxidation peak currents increased dramatically at Au-SH-SiO2@Cu-MOF. The potential utility of the sensor was demonstrated by applying it to the analytical determination of L-cysteine concentration. The results showed that the electrocatalytic current increased linearly with the L-cysteine concentration in the range of 0.02–300 μM and the detection limit was 0.008 μM. Finally, the sensor was applied to determine L-cysteine in water and biological samples.
پژوهشگران	هادی حسینی (نفر اول)، علی دهقانی (نفر دوم)، حمید احمر (نفر سوم)، آکبر باقری (نفر چهارم)، علیرضا فخاری (نفر پنجم)، آزاده تجردی (نفر ششم به بعد)