عنوان	Novel one-pot synthesis of new derivatives of dihydropyrimidinones, unusual multisubstituted imidazoline-2-ones: X-ray crystallography structure
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	Dihydropyrimidinones, ZnCl2, AlCl3:ZnCl2 (3:1), Imidazoline-2-one derivatives, X-Ray data, One-pot multicomponent reaction
چکیده	Three-component condensation of phenylglyoxal, alkyl acetoacetates or acetylacetone and urea proceeds smoothly, catalyzed by ZnCl2, to afford the corresponding new 3,4- dihydropyrimidinones. This reaction is also catalyzed by AlCl3:ZnCl2 (3:1) under microwave irradiation in solvent-free conditions. One-pot three-component condensation of dimethyl urea, acetylacetone or alkyl acetoacetate and phenylglyoxal catalyzed by ZnCl2 or AlCl3:ZnCl2 (3:1) yields new multisubstituted imidazoline-2-ones derivatives. Structures of products were studied by X-ray crystallographic data. The reaction of phenylglyoxal, urea and β-ketoesters in the presence of hydrochloric acid produces only 5-phenylhydantoins.
پژوهشگران	سعید بلالایی (نفر اول)، محمد سلیمان بیگی (نفر دوم)، فرانک رومینگر (نفر سوم)