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چکیده
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Introduction: Obesity and overweight lead to increased oxidative stress activity, disrupted lipid profiles, and elevated blood pressure. This study aimed to investigate the effects of aerobic exercise combined with crocin supplementation on metabolic syndrome indices, oxidative stress, and blood pressure in overweight/obese women. Methods: Forty overweight/obese women aged 30-40 years were randomly divided into four groups (n=10 each): aerobic exercise, crocin supplementation, exercise + supplementation, and control (placebo). In a fasted state and 24 hours before protocol initiation, blood pressure was measured, followed by collection of 5mL blood samples from the brachial vein. Pre-test measurements included metabolic syndrome indices and oxidative stress markers. The exercise groups completed an 8-week aerobic training protocol (three 40-50 minute sessions/week at 65-80% maximum heart rate), while supplementation groups received 30mg daily crocin. Post-test measurements were conducted 48 hours after the final exercise session. Results: Significant differences were observed among the four groups for weight, body fat percentage, BMI, WHR, glucose, insulin, MDA, GPX, and DBP. Bonferroni post-hoc analysis revealed these differences existed between the control group and the three intervention groups. SOD and SBP showed significant differences not only between control and intervention groups but also between the exercise and exercise + supplement groups, and between the supplement and exercise + supplement groups. Conclusion: Crocin supplementation and aerobic exercise led to significant improvements in metabolic syndrome indices, oxidative stress markers, and blood pressure in overweight/obese women. Their combined use demonstrated enhanced benefits.
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