عنوان	Diastereoselective and one-pot synthesis of trans-isoquinolonic acids via three-component condensation of homophthalic anhydride, aldehydes, and ammonium acetate catalyzed by aspartic acid
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	Isoquinolonic acid Diastereoselective Aldehyde Homophthalic anhydride Ammonium acetate
چکیده	Aspartic acid has been developed as a versatile and highly efficient organocatalyst for the three component combination of homophthalic anhydride, aldehydes, and ammonium acetate to afford transisoquinolonic acids. The reactions were carried out in acetonitrile under reflux conditions. Aspartic acid as an efficient organocatalyst exhibits dramatically improved diastereoselectivity compared with previously reported catalysts for this synthetic strategy.
پژوهشگران	آرش قربانی چقامارانی (نفر اول)، مریم حجامی (نفر دوم)، معصومه نوروزی (نفر سوم)، یونس عباسی (نفر چهارم)