عنوان	Bovine Serum Albumin-Loaded Chitosan Particles: An Evaluation of Effective Parameters on Fabrication, Characteristics, and in Vitro Release in the Presence of Non-Covalent Interactions
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	drug release, entrapment efficiency, non-covalent interactions, turbidimetry, W/O microemulsion
چکیده	BSA-loaded chitosan particles were produced using a W/O microemulsion composed of isooctane as a solvent, 1-hexanol as a co-solvent, and cetyltrimethylammonium bromide (CTAB) as a surfactant. The purpose of the current study was to investigate the effects of non-covalent interactions of BSA as a protein, chitosan as a polysaccharide, and CTAB on fabrication of BSA-loaded chitosan particles, characteristics and release profile, and the presence in the W/O microemulsion was investigated using a turbidimeter. The interactions caused an increase in the average size of the particles ranging from 1.61 to 2.05 µm and were effective on the release behaviors.
پژوهشگران	مرتضی حسن زاده کفشگری (نفر اول)، محسن منصوری (نفر دوم)، محمد خرم (نفر سوم)، عبدالرضا صمیمی (نفر چهارم)، شهریار عصفوری (نفر پنجم)