عنوان
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An improved and one-pot procedure to the synthesis of symmetric amines by domino reactions of 5-methyl-1,3,4-thiadiazole-2-
amine, a new nitrogen atom donor, and alkyl halides
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نوع پژوهش
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مقاله چاپشده در مجلات علمی
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کلیدواژهها
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C–N bond formation Selective N-alkylation Aliphatic amines 5-Methyl-1,3,4-thiadiazole-2-amine Nitrogen-transfer reagent
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چکیده
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A new one-pot method has been introduced in this work for the synthesis of symmetrical primary, secondary, and tertiary alkyl amines from alkyl halides and 5-methyl-1,3,4-thiadiazole-2-amine as a nitrogen-transfer reagent. In this method, all three types of amines have been successfully prepared after changing the ratio of substrates and base control. In addition to the introduction of a new nitrogen-transfer reagent, other important features of this work include normal atmospheric conditions and excellent yields under mild reaction conditions.
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پژوهشگران
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محمد سلیمان بیگی (نفر اول)، فریبا محمدی (نفر دوم)
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