عنوان
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Chemoselective and Catalytic Trimethylsilylation of Alcohols and Phenols by 1,1,1,3,3,3-Hexamethyldisilazane and Catalytic Amounts of PhMe3N+Br3
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نوع پژوهش
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مقاله چاپشده در مجلات علمی
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کلیدواژهها
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phenyltrimethylammonium tribromide; alcohol; phenol; protection; trimethylsilylation; hexamethyldisilazane
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چکیده
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Abstract An efficient procedure for the trimethylsilylation of alcohols and phenols is presented. The combination of 1,1,1,3,3,3-hexamethyldisilazane and a catalytic amount of phenyltrimethylammonium tribromide (PhMe3N+Br3 −) was found to be effective for the trimethylsilylation of alcohols and phenols. The protection reaction is very simple and homogenously performed in dichloromethane at room temperature and mild conditions.
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پژوهشگران
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آرش قربانی چقامارانی (نفر اول)، نسرین چراغی فتج آباد (نفر دوم)
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