عنوان	An electrochemical chlorpyrifos aptasensor based on the use of a glassy carbon electrode modified with an electropolymerized aptamer-imprinted polymer and gold nanorods
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	o-Dihydroxybenzene . o-Phenylenediamine . Hexacyanoferrate . Nanohybrid . Differential pulse voltammetry . Electrochemical impedance spectroscopy . Pesticide
چکیده	A highly selective and sensitive aptasensor is described for voltammetric determination of the pesticide chlorpyrifos (CPS). The sensor was constructed by modifying a glassy carbon electrode (GCE) with gold nanorods and a polymer that was molecularly imprinted with an aptamer against CPS. This results in double specific recognition. Under optimal conditions and a working potential as low as 0.22 V (vs. Ag/AgCl), the nanotools has a dynamic range that covers the 1.0 fM - 0.4 pM CPS concentration range, and the detection limit is 0.35 fM. This is lower than any of the previously reported methods. This MIP-aptasensor is selective over structural analogs, stable, and adequately reproducible. It was successfully applied to the determination of CPS in spiked food samples.
پژوهشگران	محمود روشنی (نفر اول)، عزیزالله نژادعلی (نفر دوم)، زینب جلیلیان (نفر سوم)