عنوان
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A glassy carbon electrode with electrodeposited silver
nanoparticles for aptamer based voltammetric determination
of trinitrotoluene using riboflavin as a redox probe
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نوع پژوهش
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مقاله چاپشده در مجلات علمی
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کلیدواژهها
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TNT . Aptasensor . AgNPs . Electrodeposition . Aptasensig assay
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چکیده
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An electrochemical nanoaptasensor is described that is based on the use of a glassy carbon electrode (GCE) modified with electrodeposited silver nanoparticles (AgNPs). An aptamer (Apt) against trinitrotoluene (TNT) was then immobilized on the AgNPs. The addition of TNT to the modified GCE leads to decrease in peak current (typically measured at a potential of −0.45 V vs. Ag/AgCl) of riboflavin which acts as an electrochemical probe. Even small changes in the surface (as induced by binding of Apt to TNT) alter the interfacial properties. As a result, the LOD is lowered to 33 aM, and the dynamic range extends from 0.1 fM to 10 μM without sacrificing specificity
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پژوهشگران
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محمود روشنی (نفر اول)، فائزه شهدوست فرد (نفر دوم)
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