عنوان	Al-Mo nanocomposite functionalization for membrane-basedresonance detection of bovine Herpesvirus-1
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	AlMo membrane,4-formylbenzene diazonium,hexafluorophosphate,Bovine herpesvirus-1,Biosensor
چکیده	tThe functionalization of a nanocomposite AlMo surface with a bifunctional diazonium linker is pre-sented. Binding of diazonium molecules to the AlMo surface was validated through XPS measurementsof 4-bromobenzenediazonium tetrafluoroborate and the linking molecule 4-formylbenzene diazoniumhexafluorophosphate. The linker was then used to bind monoclonal antibodies specific for bovineherpesvirus-1 (BHV-1) to the AlMo coated chips. BHV-1 was successfully captured on the chip surface.The functionalization process was then implemented on 10 nm thick AlMo membranes and resonancemeasurements were performed to successfully detect BHV-1. A method for calculating the mass of BHV-1on the surface of the membranes is presented and validated via finite element analysis.
پژوهشگران	Remko van den Hurka (نفر اول)، مسعود باقلانی (نفر دوم)، Jie Chena (نفر سوم)، Mojgan Daneshmanda (نفر چهارم)، Stephane Evoyaa (نفر پنجم)