عنوان	A green ultrasonic-assisted liquid–liquid microextraction based on deep eutectic solvent for the HPLC-UV determination of ferulic, caffeic and cinnamic acid from olive, almond, sesame and cinnamon oil
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	Deep eutectic solvent
چکیده	A simple,inexpensiveandsensitiveultrasonic-assistedliquid–liquidmicroextractionmethodbasedon deep eutecticsolvent(UALLME-DES)wasusedfortheextractionofthreephenolicacids(ferulic,caffeic and cinnamic)fromvegetableoils.Inatypicalexperiment,deepeutecticsolventasgreenextraction solventwasaddedton-hexane(asatypicaloilmedium)containingtargetanalytes.Subsequently,the extractionwasacceleratedbysonication.Aftertheextraction,phaseseparation(DESrichphase/n-hex- ane phase)wasperformedbycentrifugation.DESrichphase(lowerphase)waswithdrawnbyamicro- syringe andsubmittedtoisocraticreverse-phaseHPLCwithUVdetection.Underoptimumconditions obtained byresponsesurfacemethodology(RSM)anddesirabilityfunction(DF),themethodhasgood linear calibrationranges(between1.30and1000 mg L 1), coefficients ofdetermination(r240.9949)and low limitsofdetection(between0.39and0.63 mg L 1). Thisprocedurewassuccessfullyappliedtothe determination oftargetanalytesinolive,almond,sesameandcinnamonoilsamples.Therelativemean recoveriesrangedfrom94.7%to104.6%.
پژوهشگران	طاهره خزلی (نفر اول)، علی دانشفر (نفر دوم)، رضا صحرایی (نفر سوم)