عنوان	Rationally designed of hollow nitrogen doped carbon nanotubes double shelled with hierarchical nickel hydroxide nanosheet as a high performance surface substrate for cortisol aptasensing
نوع پژوهش	مقاله چاپ‌شده در مجلات علمی
کلیدواژه‌ها	Hollow nanostructures Carbon nanotubes Nickle hydroxide nanosheets Aptasensor Cortisol detection
چکیده	The development of advanced electrode materials based on hollow metal hydroxide nanosheets/carbonaceous nanostructures that have unique chemical/physical properties and sizeable inherent cavity to load specific chemical, has attracted immense attention. Herein, novel metal hydroxide nanosheets/carbonaceous nanostructures based on hollow mesoporous Ni(OH)2 nanosheet double shelled on hollow nitrogen doped carbon nanotubes (Ni(OH)2@N–C n-Tube) were designed. The N–C n-Tube skeleton was derived from its corresponded Fe2O3 nanorod with a simple self-polymerizing method, followed by an annealing and etching method. This advanced core-double shell array with ordered hierarchical Ni(OH)2 nano-architectures was successfully used as a high performance surface substrate for cortisol (COR) aptasensing. The Ni(OH)2@N–C n-Tube shows unique characteristics including high surface area with rich functional group for bonding and fixing aptamer when used as a surface substrate. This proposed aptasensor can detect COR in a linear concentration between 1 pM to 80 pM and 0.1 nM to 25 nM with a detection limit of 0.3 pM and good selectivity in the presence of various interferences
پژوهشگران	محمود روشنی (نفر اول)، هادی حسینی (نفر دوم)، زینب حاجی نیا (نفر سوم)