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چکیده
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In this work, a novel heterogeneous catalyst of Cu(ІІ) complex on modified mesoporous KIT-6 (KIT-6@DABP@Cu) was prepared via simple and inexpensive procedure using commercially available materials. The prepared catalyst was characterized by FT-IR, XRD, TGA, AAS, SEM, EDX and BET techniques. 5-Substituted tetrazoles were synthesized using nitriles and sodium azide in the presence of KIT-6@DABP@Cu catalyst in PEG as green solvent. Because, tetrazoles were used in drugs and they are used as analgesics, herbicides, antimicrobial, anti-proliferative, anti-inflammatory, and anticancer agents [1-3]. For example, Valsartan, Losartan, Candesartan and TAK-456 are several pharmacologically important of tetrazoles [4-6].
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