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Arash Ghorbani-Choghamarani

Academic rank: Professor
ORCID:
Education: PhD.
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Faculty: Basic Science
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Research

Title
Multicomponent synthesis of bioactive 1-amidoalkyl-2-naphtols under solvent-free conditions
Type
JournalPaper
Keywords
L-Pyrrolidine-2-carboxylic acid-4-hydrogen sulfate; Multicomponent reaction; Amidoalkyl naphtols; Solvent-free.
Year
2015
Journal Bulgarian Chemical Communications
DOI
Researchers Maryam Hajjami ، Arash Ghorbani-Choghamarani ، Fatemeh Gholamian

Abstract

A one-pot condensation reaction of 2-naphthol, aromatic aldehydes, and acetamide or thioacetamide catalyzed by Lpyrrolidine-2-carboxylic acid-4-hydrogen sulfate (supported on silica gel) to afford 1-amidoalkyl-2-naphthols under solvent-free conditions is described. The advantages of this method are good yields, easy work-up, mild and solventfree conditions and inexpensive catalyst.