2025 : 9 : 29

Arash Ghorbani-Choghamarani

Academic rank: Professor
ORCID:
Education: PhD.
ScopusId:
HIndex:
Faculty: Basic Science
Address:
Phone:

Research

Title
1,3-Dibromo-5,5-dimethylhydantoin as an efficient catalyst for synthesis of thioamidoalkyl and bis(thio)amidoalkyl-2-naphthols under solvent-free conditions
Type
JournalPaper
Keywords
1,3-Dibromo-5,5-dimethylhydantoin (DBH) Multicomponent reaction Thioacetamide Thioamidoalkyl naphthol Solvent-free
Year
2015
Journal RESEARCH ON CHEMICAL INTERMEDIATES
DOI
Researchers Arash Ghorbani-Choghamarani ، Shima Rashidimoghadam

Abstract

An efficient and easy method for one-pot three-component synthesis of thioamidoalkyl and bis(thio)amidoalkyl naphthols by condensation of aromatic aldehydes, 2-naphthol, and acetamide or thioacetamide under thermal condition at 130 C in the presence of 1,3-dibromo-5,5-dimethylhydantoin is described. The present approach offers several advantages such as reduced reaction time, higher yield, and economic availability of the catalyst.