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Arash Ghorbani-Choghamarani

Academic rank: Professor
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Education: PhD.
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Faculty: Basic Science
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Research

Title
An Efficient Procedure for the Synthesis of Hantzsch 1,4-Dihydropyridines Under Mild Conditions
Type
JournalPaper
Keywords
1,4-Dihydropyridines; ethyl propiolate; methyl acetoacetate; ammonium acetate; solvent-free conditions
Year
2008
Journal acta chimica slovenica
DOI
Researchers Arash Ghorbani-Choghamarani ، Mohammad Ali Zolfigol ، Peyman Salehi ، Ezat Ghaemi ، Elaheh Madrakian ، Hossein Nasr-Isfahanid ، Mozhjgan Shahamirian

Abstract

A simple and efficient one-pot synthesis of 1,4-dihydropyridine derivatives was achieved via condensation of methyl acetoacetate or ethyl propiolate with various alkyl and aryl aldehydes and ammonium acetate at 80 degrees C under solvent free conditions with good to excellent yields.