A palladium S‐benzylisothiourea complex was anchored on functionalized MCM‐41 (Pd‐SBT@MCM‐41) and applied as efficient and reusable catalyst for the synthesis of 5‐substituted 1H–tetrazoles using [2 + 3] cycloaddition reaction of various organic nitriles with sodium azide (NaN3) in poly(ethylene glycol) (PEG) as green solvent. Also this catalyst was applied as an versatile organometallic catalyst for Suzuki cross‐coupling reaction of aryl halides and phenylboronic acid (PhB(OH)2) or sodium tetraphenyl borate (NaB(Ph)4). This nanocatalyst was characterized by thermal gravimetric analysis (TGA), X‐ray Diffraction (XRD), scanning electron microscopy (SEM), inductively Coupled Plasma (ICP) and N2 adsorption–desorption isotherms techniques. Recovery of the catalyst is easily achieved by centrifugation for several consecutive runs.
