Understanding of transport parameters in nanofiltration membrane is critical for effective membrane and system design. In this study, the removal of anions using nanofiltration membrane process and the main parameters of membrane separation were investigated. The removal of Cl- and SO4-2 with the purpose to understandthe transport parameters in the Nanofiltration membrane were studied. Thestudyhasbeencarriedoutwiththe NF (DowFilmtec)membrane.Theeffectofoperatingpressure(1–10 bar) onthemembraneseparation performance hasbeeninvestigated. Then, the membrane performance was evaluated based on three transport parameters the water permeability (L_P), the salt transmittance (ϕ) and the effective salt transfer coefficient (K_eff). Rejection of sulfate was nearly 100% and the salt transmittance was obtained about 2.282%.