Fascioliasis is a disease that has been described extensively in Iran and the most countries. In the animal's livers parasitized by Fasciola hepatica, we know that they are condemned unfit for human consumption. Recent appointments indicate that it is also an emerging human parasitic disease, with about 2, 5 million affected worldwide by 2009. In order to know the current status of this parasite in the country, we decided to carry out this investigation. A retrospective study was carried out based on the existent registrations of fasciolosis discoveries in the bovine slaughterhouse of Ilam province in Iran during 3 years successively. In the year of (07-08), the totals of 2734 animals were sacrificed and 232 of the animal’s livers were infested with F. hepatica (8, 48% of the sacrificed animals). Being the year of (08-09) the total of 4059 animals were sacrificed and 245 livers were infested with F. hepatica (6, 03%), and the one with better results. The third years (09-10) the total of 2028 animals were sacrificed and 225 of livers were infested with F. hepatica (11, 09%). The affectations per year were variable mainly in Ilam province. The economic losses were considerable, being calculated, only by concept of confiscated livers in $ 100000 (USD) during the studied period. During the study period (2007-2010) found a high prevalence of fasciolosis in animals slaughtered in the province, rising to more than one third of the total, with significant differences in proportions (p<0,01) between three years. The confiscations of livers were also high, resulting in economic losses.