A highly efficient procedure for the one-pot synthesis of polysubstituted pyrrole derivatives by the reaction between of aniline derivatives, β-diketones or β-ketoesters, and β-nitrostyrene derivatives in the presence of Fe3O4@SiO2–CPTMS-guanidine–SO3H as a reusable magnetic nanocatalyst is reported. The magnetic nanocatalyst was prepared and fully characterized by FTIR spectroscopy, scanning electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffraction analysis, thermogravimetric analysis, and vibrating sample magnetometry.
