This paper reports a highly sensitive, non-invasive sensor for real-time glucose monitoring fro interstitial fuid. The structure is comprised of a chip-less tag sensor which may be taped over the patient’s skin and a reader, that can be embedded in a smartwatch. The tag sensor is energized through the established electromagnetic coupling between the tag and the reader and its frequency response is refected on the spectrum of the reader in the same manner. The tag sensor consumes zero power as there is no requirement for any active readout or communication circuitry on the tag side.