First Catalyst- and Solvent-Free Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones and -thiones

Research

Title	First Catalyst- and Solvent-Free Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones and -thiones
Type	JournalPaper
Keywords	ONE-POT SYNTHESIS; CALCIUM-CHANNEL BLOCKERS; BIGINELLI REACTION; EFFICIENT SYNTHESIS; MICROWAVE IRRADIATION; SULFURIC-ACID; CONDENSATION REACTION; REUSABLE CATALYST; CHLORIDE; ALUMINA
Year	2016
Journal	RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
DOI
Researchers	Maryam Hajjami ، Elahe Ghiasbeygi

Abstract

A completely green and environmentally benign Biginelli synthesis of 3,4-dihydropyrimidine- 2(1H)-ones and -thiones by one-pot three-component reaction of aromatic aldehydes with ethyl acetoacetate and urea or thiourea without any catalyst under solvent-free conditions is described

Maryam Hajjami

Research

Abstract