Amount of precipitated asphaltene be reduce considerable with pretreatment asphaltene inhibitor, into mixture of crude oil. Efficiency of asphaltene inhibitors is depend on many parameter like pH andchemical structure of asphaltene inhibitors In this paper. The amounts of asphaltene precipitation have been measured using seven n-heptane as precipitants. The onset points has been determined using asphaltene inhibitor with pH=3.8. the result show that adding 465 ppm of acidic asphaltene inhibitor is optimum amount and onset point occurred in 35 vol. % of n-heptane.