The chemoselective oxidative coupling of thiols to disulfides and oxidation of sulfides to corresponding sulfoxides are great procedures in organic chemistry, because disulfides and sulfoxides have important role in biological application, enzymes activation, separation of radioactive or less common metals and in medicinal chemistry. Therefore, we have investigated 5-nitro-salicylaldehyde Schiff-base complex of iron on MCM-41 (Fe-5NSA-MCM-41) as a stable, efficient, environment friendly, reusable, and chemoselective catalyst for the synthesis of disulfide and sulfoxide derivatives using hydrogen peroxide (H2O2) as an environmentally friendly, inexpensive and available oxidant. This catalyst can recovered and reused for several times without significant loss in catalytic activity.
