Two Schiff-base complexes of zirconium oxide and copper on Fe3O4 magnetic nanoparticles were synthesized. Then, their catalytic performance were developed in the synthesis of amide derivatives by reduction of nitrile to amide. These catalysts were characterized using SEM, WDX, EDS, TGA, XRD, AAS and VSM techniques. The characterized analysis confirmed that these heterogeneous catalysts are stable during the reaction process and could also be reused several times. The amide products were obtained in good to excellent yields with high purity (Scheme 1).