A newelectrochemical sensor based on copper nanoparticles for detection of hydrogen peroxide has been developed. Copper nanoparticles/Rutin/Multiwall Carbon Nanotubes/Ionic liquid/Chitosan modified glassy carbon electrode (CuNPs/Rutin/MWCNTs/IL/Chit/GCE) prepared by consecutive coating of MWCNTs/IL/Chit nanocomposite and rutin on the GCE, followed by the electrodeposition of copper. Surface physical characteristics of modified electrode were studied by scanning electron microscopy (SEM). The electrochemical performance of the sensor for detection of H2O2 was investigated by cyclic voltammetry and chronoamperometry techniques. The modified electrode exhibits an enhanced electrocatalytic property, lowworking potential, high sensitivity, excellent selectivity, good stability, and fast amperometric sensing towards reduction of hydrogen peroxide. The response to H2O2 is linear in the range between 0.35 μM to 2500 μM, and the detection limit is 0.11 μM.
