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Mohammad Soleiman-Beigi

Academic rank: Professor
ORCID:
Education: PhD.
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HIndex:
Faculty: Basic Science
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Research

Title
An improved and one-pot procedure to the synthesis of symmetric amines by domino reactions of 5-methyl-1,3,4-thiadiazole-2- amine, a new nitrogen atom donor, and alkyl halides
Type
JournalPaper
Keywords
C–N bond formation  Selective N-alkylation  Aliphatic amines  5-Methyl-1,3,4-thiadiazole-2-amine  Nitrogen-transfer reagent
Year
2017
Journal MONATSHEFTE FUR CHEMIE
DOI
Researchers Mohammad Soleiman-Beigi ، Fariba Mohammadi

Abstract

A new one-pot method has been introduced in this work for the synthesis of symmetrical primary, secondary, and tertiary alkyl amines from alkyl halides and 5-methyl-1,3,4-thiadiazole-2-amine as a nitrogen-transfer reagent. In this method, all three types of amines have been successfully prepared after changing the ratio of substrates and base control. In addition to the introduction of a new nitrogen-transfer reagent, other important features of this work include normal atmospheric conditions and excellent yields under mild reaction conditions.