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Mohammad Soleiman-Beigi

Academic rank: Professor
ORCID:
Education: PhD.
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Faculty: Basic Science
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Research

Title
Na/THF-Mediated cleavage of organic disulfides/diselenides. An efficient and one-pot regioselective method to the synthesis of β-hydroxy sulfides/selenides
Type
JournalPaper
Keywords
Epoxides; Ring opening; Disulfides; Diselenides; Catalyst-free reaction
Year
2019
Journal arabian journal of chemistry
DOI
Researchers Mohammad Soleiman-Beigi ، Homa Kohzadi

Abstract

A new, facile, and efficient methodology for synthesizing b-hydroxy sulfides/selenides has been reported. In this study, 1,2-epoxide ring opening was used as the synthetic protocol, and this reaction was examined using metallic sodium with no additional catalyst. This lead to the synthesis of the desired ring-opened products. Relatively short reaction times, mild reaction conditions, a simple work-up, moderate to good yields of products, and remarkable regioselectivity of the nucleophilic attack were other important features of this study