The local particle velocity is an important hydrodynamic parameter in the design and optimization of gas-solid systems, such as the spouted beds. Predicting the particle velocity in the spout region is often complex, and developing a simple and reliable method for estimating this parameter is both valuable and highly beneficial for engineers and system designers. In the present study, the intelligent predictive approach of a multi-layer perceptron neural network (MLP-NN) is used for the first time to investigate the feasibility of measuring the local particle velocity within the spout region of spouted beds. Accordingly, 224 measured data points are collected, covering a broad range of factors such as bed diameter, inlet diameter, static bed height, cone angle, minimum spouting velocity, and inlet gas velocity for Geldart D particles with varying densities and diameters. The data are then used for training, validating, and testing the intelligence-based model. The MLP-NN-based model shows a strong predictive capability for estimating particle velocity in the spouted bed, with an Average Absolute Relative Error (AARE) of 13.32%, an R2 value of 0.9842, and a Root Mean Squared Error (RMSE) of 0.033 for the test dataset. In addition, for all data, the model achieves an AARE of 6.30%, an RMSE of 0.0098, and an R2 value of 0.9942. Furthermore, in the present study, a sensitivity analysis is conducted on the data to determine the degree of influence of the input parameters on the target function.